Correlations between the slope as well as offset parameters of the linear regression analysis of the patient and volunteer data and physiological parameters, specifically age, height, and vascular health yield interesting results. Graph A presents the relationship between pulse pressure /T13 gain as a function of increasing heart rate variability, while graph B does the same for systolic pressure/(p2/p1). Heart rate variability has been extensively linked to vagal tone to vascular health. Succinctly put, the gains increase with decreasing vascular health because the circumferential arterial wall stress rises much faster in harder arteries than in softer arteries. It is also interesting to note that no correlations were found so far with age or height. The preliminary nature of these results due to the limited number of subjects observed so far is understood.
The graphs above present correlations between radial pulse parameters T13 (see previous page) and p2/p1, the ratio of the #2 component pulse amplitude to that of component pulse #1. In the case of the diabetic patient the correlation is with a cuff while in the case of the normo-tensive subject a continuous tonometric blood pressure monitor was used.
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Hypertensive diabetic:
Top: Cuff pulse pressure vs. P2/P1
Bottom: Cuff systolic pressure vs T13
Normo-tensive:
Top: tonometric continuous systolic pressure vs. P2/P1
Interbeat Variability (milliseconds)
Interbeat Variability (milliseconds)